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Treating Opportunistic Infections Among HIV-Infected Adults and Adolescents
Infectious Diseases - Executive Summary
The National Institutes of
Health, the HIV Medicine Association of the Infectious Diseases Society of
America, and CDC have developed guidelines for treatment of opportunistic
infections (OIs) among adults and adolescents infected with human
immunodeficiency virus (HIV). These guidelines are intended for clinicians and
other health-care providers who care for HIV-infected adults and adolescents,
including pregnant women; they complement companion guidelines for treatment of
OIs among HIV-infected children and previously published guidelines for
prevention of OIs in these populations. They include evidence-based guidelines
for treatment of 28 OIs caused by protozoa, bacteria, fungi, and viruses,
including certain OIs endemic in other parts of the world but that might be
observed in patients in the United States. Each OI section includes information
on epidemiology, clinical manifestations, diagnosis, treatment recommendations,
monitoring and adverse events, management of treatment failure, prevention of
recurrence, and special considerations in pregnancy. Tables address drugs and
doses, drug toxicities, drug interactions, adjustment of drug doses in persons
with reduced renal function, and data about use of drugs in pregnant women.
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